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Merck
모든 사진(2)

문서

850697C

Avanti

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, chloroform

동의어(들):

PE(6:0/6:0)

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About This Item

실험식(Hill 표기법):
C17H34NO8P
CAS Number:
Molecular Weight:
411.43
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 2.5 mL (850697C-25mg)

제조업체/상표

Avanti Research - A Croda Brand 850697C

농도

10 mg/mL (850697C-25mg)

지질 유형

phospholipids
cardiolipins

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O

일반 설명

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) is a phosphoethanolamine (PE) molecule which carries short acyl chains. It is an ethanolamine-type substrate and a water-soluble phospholipid.

애플리케이션

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
  • as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity studies as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
  • as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
  • as calibration standard in hydrophilic interaction liquid chromatography (HILIC) and ion mobility (IM)

생화학적/생리학적 작용

Phosphoethanolamine (PE) is known to possess antitumor activity and inhibitory effects on tumor progression in vivo. It also exhibits antiproliferative and proapoptotic effects. It acts as a precursor of phosphatidylcholine and phosphatidylethanolamine.

포장

5 mL Clear Glass Sealed Ampule (850697C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry (2020)
S F Martin et al.
Biochemistry, 39(12), 3410-3415 (2000-03-22)
The phosphatidylcholine-preferring phospholipase C from Bacillus cereus (PLC(Bc)) is a 28.5 kDa enzyme with three zinc ions in its active site. The roles that a number of amino acid residues play as zinc ligands and in binding and catalysis have
Lipidomics by HILIC-Ion Mobility-Mass Spectrometry
Ion Mobility-Mass Spectrometry, 119-132 (2020)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
Shingo Mineta et al.
Journal of bioscience and bioengineering, 119(2), 123-130 (2014-08-20)
Streptomyces sanglieri extracellularly produces a glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP). The gene encoding the enzyme was found to consist of a 2124-bp ORF, which codes for an N-terminal 48 residue signal peptide required for secretion and a 660 amino acid mature protein

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