857125C

20:4 Lyso PA

1-arachidonoyl-2-hydroxy-sn-glycero-3-phosphate (ammonium salt), chloroform

• 동의어(들): arachidonoyl lysophosphatidic acid; 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate (ammonium salt); PA(20:4(5Z,8Z,11Z,14Z)/0:0); 20:4 LPA
• 실험식(Hill 표기법): C₂₃H₄₂NO₇P
• CAS Number: 799268-65-8
• Molecular Weight: 475.56
• UNSPSC 코드: 51191904
• NACRES: NA.25

속성

• 분석: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• 양식: liquid
• 포장: pkg of 1 × 1 mL (857125C-10mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 857125C
• 농도: 10 mg/mL (857125C-10mg)
• 지질 유형: cardiolipins; phospholipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: O[C@](COP([O-])(O)=O)([H])COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[NH4+]
• InChI: 1S/C23H39O7P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)29-20-22(24)21-30-31(26,27)28;/h6-7,9-10,12-13,15-16,22,24H,2-5,8,11,14,17-21H2,1H3,(H2,26,27,28);1H3/b7-6-,10-9-,13-12-,16-15-;/t22-;/m1./s1
• InChI key: MQNJYFKSBIEJTA-PWZWHAFSSA-N

설명

일반 설명

Lysophosphatidic acid (LPA) is a lysophospholipid comprising of glycerol 3-phosphate (G3P), fatty acids, and phosphates.

애플리케이션

20:4 Lyso PA (LPA) has been used in feeding low density lipoprotein receptor null (LDLR^-/-) mice. It is suitable for use as standard for high performance liquid chromatography (HPLC) and liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) for the quantification of human plasma LPA, and as a strong agonist for lysophosphatidic acid receptor1(LPA₁).

생화학적/생리학적 작용

Lysophosphatidic acid (LPA) is a bioactive lipid produced in tissues. LPA is involved in signal transduction through G-protein coupled receptors. LPA is implicated in many diseases including atherosclerosis, ischaemia perfusion injury, thrombosis and hypertension. LPA also plays an important role in wound healing processes, autoimmune diseases and tumor metastasis.

포장

5 mL Clear Glass Sealed Ampule (857125C-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 예방조치 성명서: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 표적 기관: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash