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Key Documents

860549P

Avanti

C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z))

Avanti Research - A Croda Brand 860549P, powder

동의어(들):

D-glucosyl-β-1,1′-N-nervonoyl-D-erythro-sphingosine

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About This Item

실험식(Hill 표기법):
C48H91NO8
CAS Number:
Molecular Weight:
810.24
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 5 mg (860549P-5mg)

제조업체/상표

Avanti Research - A Croda Brand 860549P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

일반 설명

β-Glucosylceramides or glucocerebrosides (GlcCers) are synthesized from the glycosphingolipids by β-GlcCer synthase. They are synthesized in Golgi and endoplasmic reticulum and localized in the cytosolic side of cell membrane. GlcCers are omnipresent.

애플리케이션

C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z)) may be used:
  • as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
  • to test its nuclear factor of activated T-cells (NFAT) activation
  • in human natural killer T (NKT) cell potency assays

생화학적/생리학적 작용

β-Glucosylceramides (β-GlcCer) levels are elevated inlevels in Gaucher′s disease, due to the deficiency of β-glucosidase. β-GlcCer participates in the inflammatory and acquired immune responses by binding mincle on myeloid cells and has immunostimulatory activity.

포장

5 mL Amber Glass Screw Cap Vial (860549P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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