추천 제품
형태
powder
포장
pkg of 1 × 5 mg (860549P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 860549P
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
일반 설명
β-Glucosylceramides or glucocerebrosides (GlcCers) are synthesized from the glycosphingolipids by β-GlcCer synthase. They are synthesized in Golgi and endoplasmic reticulum and localized in the cytosolic side of cell membrane. GlcCers are omnipresent.
애플리케이션
C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z)) may be used:
- as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
- to test its nuclear factor of activated T-cells (NFAT) activation
- in human natural killer T (NKT) cell potency assays
생화학적/생리학적 작용
β-Glucosylceramides (β-GlcCer) levels are elevated inlevels in Gaucher′s disease, due to the deficiency of β-glucosidase. β-GlcCer participates in the inflammatory and acquired immune responses by binding mincle on myeloid cells and has immunostimulatory activity.
포장
5 mL Amber Glass Screw Cap Vial (860549P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
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Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals
Journal of Lipid Research, 58(6), 1247-1258 (2017)
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Intracellular metabolite beta-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity
Proceedings of the National Academy of Sciences of the USA, 114(16), E3285-E3294 (2017)
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