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860547P

Avanti

C18 Glucosyl(β) Ceramide (d18:1/18:0)

Avanti Research™ - A Croda Brand

동의어(들):

D-glucosyl-β-1,1′-N-stearoyl-D-erythro-sphingosine

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C42H81NO8
CAS Number:
95119-86-1
Molecular Weight:
728.09
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 100 mg (860547P-100mg)
pkg of 1 × 25 mg (860547P-25mg)
pkg of 1 × 5 mg (860547P-5mg)

제조업체/상표

Avanti Research™ - A Croda Brand

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI

1S/C42H81NO8/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-38(46)43-35(34-50-42-41(49)40(48)39(47)37(33-44)51-42)36(45)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,35-37,39-42,44-45,47-49H,3-28,30,32-34H2,1-2H3,(H,43,46)/b31-29+/t35-,36+,37?,39+,40?,41?,42+/m0/s1

InChI key

YMYQEDCYNANIPI-KNSMPFANSA-N

애플리케이션

C18 Glucosyl(β) Ceramide (d18:1/18:0) or D-glucosyl-β-1,1′-N-stearoyl-D-erythro-sphingosine has been used:
  • as a lipid standard for its quantification using differential ion mobility spectrometry (DMS) coupled with liquid chromatography in electrospray ionization tandem mass spectrometry (LC-ESI-DMS-MS/MS) in human plasma
  • in the preparation of lipid dispersions
  • used in an assay to monitor the turnover of glucosylceramide in glucocerebrosidase (GBA1) cell free system

포장

5 mL Amber Glass Screw Cap Vial (860547P-100mg)
5 mL Amber Glass Screw Cap Vial (860547P-25mg)
5 mL Amber Glass Screw Cap Vial (860547P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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문서 라이브러리 방문

Jong Hoon Won et al.
Neuroscience, 427, 1-15 (2019-11-26)
Neurotransmitter release is mediated by ceramide, which is generated by sphingomyelin hydrolysis. In the present study, we examined whether synaptosomal-associated protein 25 (SNAP-25) is involved in ceramide production and exocytosis. Neutral sphingomyelinase 2 (nSMase2) was partially purified from bovine brain
Differential mobility spectrometry as an orthogonal separation to LC-ESI-MS/MS for quantification of isomeric cerebrosides in plasma and cerebrospinal fluid
Xu H, et al.
Journal of Lipid Research, jlr-D089797 (2018)
Joseph R Mazzulli et al.
Cell, 146(1), 37-52 (2011-06-28)
Parkinson's disease (PD), an adult neurodegenerative disorder, has been clinically linked to the lysosomal storage disorder Gaucher disease (GD), but the mechanistic connection is not known. Here, we show that functional loss of GD-linked glucocerebrosidase (GCase) in primary cultures or
Hongbin Xu et al.
Journal of lipid research, 60(1), 200-211 (2018-11-11)
Cerebrosides, including glucosylceramides (GlcCers) and galactosylceramides (GalCers), are important membrane components of animal cells with deficiencies resulting in devastating lysosomal storage disorders. Their quantification is essential for disease diagnosis and a better understanding of disease mechanisms. The simultaneous quantification of
Zdenek Berger et al.
PloS one, 10(3), e0119141-e0119141 (2015-03-13)
Mutations in glucocerebrosidase (GBA1) cause Gaucher disease and also represent a common risk factor for Parkinson's disease and Dementia with Lewy bodies. Recently, new tool molecules were described which can increase turnover of an artificial substrate 4MUG when incubated with
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