추천 제품
형태
powder
포장
pkg of 1 × 5 mg (860595P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 860595P
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
일반 설명
Lactosylceramide (LacCer) is a glycosphingolipid. It consists of a hydrophobic ceramide lipid and a hydrophilic sugar moiety. LacCer is expressed abundantly in the nervous system and myelin sheath.
생화학적/생리학적 작용
Lactosylceramide (LacCer) is a structural and signaling lipid. It is implicated in signal transduction, cell adhesion and host-tissue pathogen interactions. LacCer modulates cell proliferation and apoptosis. It is involved in regulating cellular stress response and microbial pathogenesis. LacCer regulates innate immune responses. It helps in microbial attachment and also acts as an adhesion receptor for pathogens.
포장
5 mL Amber Glass Screw Cap Vial (860595P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharide, 191, 106-114 (2009)
Daniela Couto et al.
Chemistry and physics of lipids, 191, 106-114 (2015-09-01)
Galactosylceramide (GalCer) and lactosylceramide (LacCer) are structural and signaling lipids, playing important roles in signal transduction and cell adhesion. They are especially abundant in the nervous system and in important components of the myelin sheath. Although neurodegenerative disorders are associated
Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in
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