860517P

C17 Ceramide (d18:1/17:0)

Avanti Research^™ - A Croda Brand

• 동의어(들): N-heptadecanoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₃₅H₆₉NO₃
• CAS Number: 67492-16-4
• Molecular Weight: 551.93
• MDL number: MFCD02259275
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 10 mg (860517P-10mg); pkg of 1 × 25 mg (860517P-25mg); pkg of 1 × 5 mg (860517P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C35H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(39)36-33(32-37)34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-34,37-38H,3-27,29,31-32H2,1-2H3,(H,36,39)/b30-28+/t33-,34+/m0/s1
• InChI key: ICWGMOFDULMCFL-QKSCFGQVSA-N

설명

일반 설명

Ceramide synthesis is mediated either by the salvage pathway by the acylation of sphingosine or sphingolipids hydrolysis or by de novo pathway via dihydroceramide formation. Structurally, ceramides have a sphingoid base, a long-chain amino alcohol linked to fatty acid by an amide bond.

애플리케이션

C17 Ceramide (d18:1/17:0) has been used:

• as an internal standard for myocardial ceramide quantification using chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry
• as an internal standard in tandem mass spectrometry (MS/MS)
• as a substrate for sphingomyelin synthase 2 enzyme

생화학적/생리학적 작용

Ceramides play a key role in regulating various cellular processes like senescence and apoptosis. They are directly involved in the proliferation and differentiation of skin cells and regulate skin barrier functionality. Ceramide based analogs are potential anti-tumor agents and are regarded as tumor suppressor lipid.

포장

5 mL Amber Glass Screw Cap Vial (860517P-10mg)

5 mL Amber Glass Screw Cap Vial (860517P-25mg)

5 mL Amber Glass Screw Cap Vial (860517P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3