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Merck
모든 사진(2)

주요 문서

840028P

Avanti

17:0 PS

Avanti Research - A Croda Brand

동의어(들):

PS(17:0/17:0)

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About This Item

실험식(Hill 표기법):
C40H77NO10PNa
CAS Number:
Molecular Weight:
786.00
UNSPSC 코드:
51191904
NACRES:
NA.25

설명

1,2-diheptadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt)

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 10 mg (840028P-10mg)
pkg of 1 × 25 mg (840028P-25mg)

제조업체/상표

Avanti Research - A Croda Brand

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(42)48-33-36(34-49-52(46,47)50-35-37(41)40(44)45)51-39(43)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h36-37H,3-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/t36-,37+;/m1./s1

InChI key

HNPCQASYRKKJRQ-JBEIVTSCSA-M

일반 설명

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

애플리케이션

17:0 PS has been used as an internal standard for BXD liver and plasma sample analysis. It may be used as a standard to estimate the cellular lipidome of Saccharomyces cerevisiae by liquid chromatography coupled with tandem mass spectrometry.

생화학적/생리학적 작용

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

포장

5 mL Amber Glass Screw Cap Vial (840028P-10mg)
5 mL Amber Glass Screw Cap Vial (840028P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Karamat Mohammad et al.
Journal of visualized experiments : JoVE, (157) (2020-03-24)
Lipids are structurally diverse amphipathic molecules that are insoluble in water. Lipids are essential contributors to the organization and function of biological membranes, energy storage and production, cellular signaling, vesicular transport of proteins, organelle biogenesis, and regulated cell death. Because
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Pooja Jha et al.
Cell systems, 6(6), 722-733 (2018-06-18)
The genetics of individual lipid species and their relevance in disease is largely unresolved. We profiled a subset of storage, signaling, membrane, and mitochondrial liver lipids across 385 mice from 47 strains of the BXD mouse population fed chow or
Rose M Gathungu et al.
Analytical chemistry, 90(22), 13523-13532 (2018-09-29)
Lipidomics requires the accurate annotation of lipids in complex samples to enable determination of their biological relevance. We demonstrate that unintentional in-source fragmentation (ISF, common in lipidomics) generates ions that have identical masses to other lipids. Lysophosphatidylcholines (LPC), for example
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic

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