860662P

Sphingosine-1-Phosphate (d20:1)

Avanti Research^™ - A Croda Brand 860662P, powder

• 동의어(들): D-erythro-sphingosine-1-phosphate (C20 base)
• 실험식(Hill 표기법): C₂₀H₄₂NO₅P
• CAS Number: 799812-75-2
• Molecular Weight: 407.52
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 형태: powder
• 포장: pkg of 1 × 1 mg (860662P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860662P
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O
• InChI: 1S/C20H42NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h16-17,19-20,22H,2-15,18,21H2,1H3,(H2,23,24,25)/b17-16+/t19-,20+/m0/s1
• InChI key: YUUWWSOTAGQJFW-YIVRLKKSSA-N

설명

일반 설명

Sphingosine-1-phosphate (S1P) is a zwitterionic sphingolipid. It is found in insects, yeasts and plants. Sphingosine-1-Phosphate (d20:1) is a phosphorylated derivative of long chain base C20 sphingosine.

애플리케이션

Sphingosine-1-phosphate (S1P)-d7 has been used as a reference standard in liquid chromatography/tandem mass spectrometry analysis for quantitative analyses of S1P d20:1 in central nervous system of healthy mice and in human glioblastoma tissue.

생화학적/생리학적 작용

Sphingosine-1-phosphate (S1P) is an important cellular metabolite and signaling lipid in animal cells. It aids in various physiological and cellular processes such as atherosclerosis, inflammation, immunity, tumorigenesis, and cell proliferation. S1P plays a vital role in mammalian brain and cardiac development. S1P d20:1 serves as a partial agonist at the S1P receptor 2 (S1P2). It has an ability to inhibit S1P d18:1‐mediated cyclooxygenase 2(COX2) induction.

포장

5 mL Amber Glass Screw Cap Vial (860662P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3