890000P
Avanti
MVL5
Avanti Research™ - A Croda Brand 890000P, powder
동의어(들):
N1-[2-((1S)-1-[(3-aminopropyl)amino]-4-[di(3-amino-propyl)amino]butylcarboxamido)ethyl]-3,4-di[oleyloxy]-benzamide
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C59H116Cl5N7O4
CAS Number:
Molecular Weight:
1164.86
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
형태
powder
포장
package of 1 × 1 mg (890000P-1mg)
package of 1 × 5 mg (890000P-5MG)
제조업체/상표
Avanti Research™ - A Croda Brand 890000P
응용 분야
advanced drug delivery
지질 유형
transfection
cationic lipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
CCCCCCCC/C=C\CCCCCCCCOC1=C(OCCCCCCCC/C=C\CCCCCCCC)C=C(C(NCCNC(C([NH2+]CCC[NH3+])CCC[N+](CCC[NH3+])([H])CCC[NH3+])=O)=O)C=C1.[5Cl-]
애플리케이션
MVL5 has been used in liposome preparation.
생화학적/생리학적 작용
MVL5 is a cationic lipid and is a pentavalent molecule. It is combined with 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (DOPC) in liposome formulation, for efficient gene transfection. It is considered less toxic.
포장
5 mL Amber Glass Screw Cap Vial (890000P-1MG)
5 mL Amber Glass Screw Cap Vial (890000P-5MG)
5 mL Amber Glass Screw Cap Vial (890000P-5MG)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
No data available
Flash Point (°C)
No data available
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Chia-Ling Chan et al.
The journal of gene medicine, 16(3-4), 84-96 (2014-04-23)
Cationic liposome (CL)-DNA complexes are promising gene delivery vectors with potential application in gene therapy. A key challenge in creating CL-DNA complexes for application is that their transfection efficiency (TE) is adversely affected by serum. In particular, little is known
Endosomal escape and transfection efficiency of PEGylated cationic liposome-DNA complexes prepared with an acid-labile PEG-lipid
Chan CL, et al.
Biomaterials, 33(19), 4928-4935 (2012)
Nathan F Bouxsein et al.
Biochemistry, 46(16), 4785-4792 (2007-03-30)
Small interfering RNAs (siRNAs) of 19-25 bp mediate the cleavage of complementary mRNA, leading to post-transcriptional gene silencing. We examined cationic lipid (CL)-mediated delivery of siRNA into mammalian cells and made comparisons to CL-based DNA delivery. The effect of lipid
Asymmetric cationic liposomes designed for heat-activated association with cells
Jing Y, et al.
Colloids and Surfaces. B, Biointerfaces, 151, 112-118 (2017)
Cecília Leal et al.
Langmuir : the ACS journal of surfaces and colloids, 27(12), 7691-7697 (2011-05-27)
The self-assembly of a custom-synthesized pentavalent cationic lipid (MVL5) and glycerol monooleate (GMO) with small interfering RNA (siRNA) results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains as shown by synchrotron X-ray scattering and
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