890899C

DODMA

Avanti Research^™ - A Croda Brand

• 동의어(들): 1,2-Dioleyloxy-3-dimethylaminopropane
• 실험식(Hill 표기법): C₄₁H₈₁NO₂
• CAS Number: 104162-47-2
• Molecular Weight: 620.09
• MDL number: MFCD22200991
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: chloroform solution
• 포장: pkg of 1 × 4 mL (890899C-100MG); pkg of 5 × 4 mL (890899C-500MG)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 농도: 25 mg/mL in chloroform
• 응용 분야: advanced drug delivery
• 지질 유형: cationic lipids; transfection
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CN(C)CC(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC
• InChI: 1S/C41H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,41H,5-18,23-40H2,1-4H3
• InChI key: GLGLUQVVDHRLQK-UHFFFAOYSA-N

설명

일반 설명

DODMA (1,2-dioleyloxy-3-dimethylaminopropane) is an ionizable cationic lipid. DODMA possesses one double bond in each hydrocarbon tail with tertiary amine group and has a pKa of 7.0.

애플리케이션

DODMA is suitable for use in the preparation of lipid nanoparticles (LNPs).

생화학적/생리학적 작용

DODMA (1,2-dioleyloxy-3-dimethylaminopropane) is used in the preparation of cationic liposomes and lipid nanoparticles (LNPs). LNPs with DODMA has low or neutral zeta potential. DODMA is efficient in encapsulating nucleic acid during synthesis by reducing the physiological pH. DODMA is implicated in gene therapy.

포장

5 mL Clear Glass Sealed Ampule (890899C-100MG)
5 × 5 mL Clear Glass Sealed Ampule (890899C-500MG)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372
• 예방조치 성명서: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable