H-101

trans-3′-Hydroxycotinine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₁₀H₁₂N₂O₂
• CAS Number: 34834-67-8
• Molecular Weight: 192.21
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 형태: liquid
• 특징: (Snap-N-Spike^®)
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: CN1[C@H](C2=CN=CC=C2)C[C@@H](O)C1=O
• InChI: 1S/C10H12N2O2/c1-12-8(5-9(13)10(12)14)7-3-2-4-11-6-7/h2-4,6,8-9,13H,5H2,1H3/t8-,9+/m0/s1
• InChI key: XOKCJXZZNAUIQN-DTWKUNHWSA-N

설명

일반 설명

Trans-3′-Hydroxycotinine is a major nicotine metabolite excreted in the urine of smokers and users of other tobacco or nicotine products including cigars, chewing tobacco and snuff. This Certified Spiking Solution^® is suitable for use in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers by LC-MS/MS or GC/MS.

애플리케이션

• Wastewater-Based Tobacco Use Estimates: trans-3′-Hydroxycotinine is used as WBE biomarkers to to estimate tobacco use. It has significantly improved wastewater-based tobacco use estimates. This application enhances our understanding of public health trends by providing more accurate measurements of tobacco consumption in populations, using advanced environmental monitoring techniques (Zheng et al., 2023).


• Predicting Nicotine Metabolism: Trans-3′-Hydroxycotinine is utilized in genomic studies to predict nicotine metabolism across different ancestries, which helps in tailoring smoking cessation therapies based on individual genetic profiles.(Baurley et al., 2022).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 49.5 °F
• Flash Point (°C): 9.7 °C