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Merck
모든 사진(1)

문서

05-1108

Sigma-Aldrich

Anti-Insulin Antibody, clone1

clone MAB1, from mouse, purified by affinity chromatography

동의어(들):

Anti-IDDM, Anti-IDDM1, Anti-IDDM2, Anti-ILPR, Anti-IRDN, Anti-MODY10, Anti-PNDM4

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

MAB1, monoclonal

정제법

affinity chromatography

종 반응성

human

기술

immunohistochemistry: suitable (paraffin)

동형

IgG1

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... INS(3630)

일반 설명

Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism.

특이성

This antibody recognizes an epitope including the amino acid B30.

면역원

Biosynthetic human insulin

애플리케이션

Anti-Insulin Antibody, clone1 is an antibody against Insulin for use in IH(P).
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

품질

Evaluated by Immunohistochemistry in human pancreas tissue.
Immunohistochemistry Analysis: 1.25 µg/mL of this antibody detected insulin in human pancreas tissue.

표적 설명

Approx. 12 kDa

결합

Replaces: CBL71

물리적 형태

Affinity purified
The monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

저장 및 안정성

Store at 2-8°C and use within 1 year from date of receipt.

분석 메모

Control
Human pancreas tissue.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Gladys Teitelman
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 68(10), 691-702 (2020-10-02)
In pancreatic beta cells, proinsulin (ProIN) undergoes folding in endoplasmic reticulum/Golgi system and is translocated to secretory vesicles for processing into insulin and C-peptide by the proprotein convertases (PC)1/3 and PC2, and carboxypeptidase E. Human beta cells show significant variation
Renaud Jacquemart et al.
Computational and structural biotechnology journal, 14, 309-318 (2016-08-30)
The current processing paradigm of large manufacturing facilities dedicated to single product production is no longer an effective approach for best manufacturing practices. Increasing competition for new indications and the launch of biosimilars for the monoclonal antibody market have put

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