05-1938
Anti-G3BP1 Antibody, clone 14E5-G9
clone 14E5-G9, from mouse
동의어(들):
ATP-dependent DNA helicase VIII, GAP SH3 domain-binding protein 1, GAP binding protein, GTPase activating protein (SH3 domain) binding protein 1, Ras-GTPase-activating protein SH3-domain-binding protein, RasGAP-associated endoribonuclease G3BP
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
클론:
14E5-G9, monoclonal
application:
ICC
WB
WB
종 반응성:
human
기술:
immunocytochemistry: suitable
western blot: suitable
western blot: suitable
citations:
1
추천 제품
생물학적 소스
mouse
Quality Level
항체 생산 유형
primary antibodies
클론
14E5-G9, monoclonal
종 반응성
human
기술
immunocytochemistry: suitable
western blot: suitable
동형
IgG1κ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... G3BP1(10146)
일반 설명
G3BP1 (Ras-GTPase activating protein SH3-domain binding protein 1) directly associates with SH3 domains of GTPase activating proteins (GAPs). It was first discovered by its binding to RasGAP. G3BPs have been shown to be involved in a number of mitogenic signaling pathways. G3BP1 is also known to be over expressed in many human cancers (Kim, 2007) and its expression appears to be inversely correlated with PTEN expression (Kim, 2007). Interestingly, G3BP1, along with G3BP2, has been shown to bind to the C-terminus of p53, playing a crucial role in its activity (Kim, 2007). Furthermore, the G3BPs have two traditional RNA binding motifs.
특이성
This antibody recognizes G3BP1.
면역원
GST-tagged recombinant protein corresponding to human G3BP1.
애플리케이션
Anti-G3BP1 Antibody, clone 14E5-G9 is an antibody against G3BP1 for use in WB & IC.
Research Sub Category
RNA Metabolism & Binding Proteins
G-proteins
RNA Metabolism & Binding Proteins
G-proteins
품질
Evaluated by Western Blot in K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
표적 설명
52 kDa
물리적 형태
Format: Purified
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Yu Sun et al.
Nature communications, 11(1), 3354-3354 (2020-07-06)
Expansion of an intronic (GGGGCC)n repeat region within the C9orf72 gene is a main cause of familial amyotrophic lateral sclerosis and frontotemporal dementia (c9ALS/FTD). A hallmark of c9ALS/FTD is the accumulation of misprocessed RNAs, which are often targets of cellular
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