추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
99D, monoclonal
종 반응성
rat, human, mouse
제조업체/상표
Upstate®
기술
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1κ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... BIN1(274)
mouse ... Bin1(30948)
특이성
Bin1
면역원
Partial fusion protein corresponding to amino acids 189-398 of human Bin1. Clone 99D
애플리케이션
Anti-Bin1 Antibody, clone 99D is an antibody against Bin1 for use in IP, WB, IH.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
품질
routinely evaluated by immunoblot on RIPA lysate of C2C12 cells.
표적 설명
56kDa
결합
Replaces: MAB4131
물리적 형태
0.1M Tris-glycine, pH 7.4, containing 0.05% sodium azide
Format: Purified
Protein G Chromatography
저장 및 안정성
1 year at -20°C
기타 정보
Due to license agreement restrictions, this product cannot be purchased for resale.
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Sisi Yang et al.
Neuron, 110(5), 824-840 (2022-01-24)
Autophagy is a cellular degradation pathway essential for neuronal health and function. Autophagosome biogenesis occurs at synapses, is locally regulated, and increases in response to neuronal activity. The mechanisms that couple autophagosome biogenesis to synaptic activity remain unknown. In this
Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Telfer, JF; Urquhart, J; Crouch, DH
Cellular Signalling null
Tiago Mendes et al.
Current protocols in cell biology, 86(1), e100-e100 (2019-12-27)
The proximity ligation assay (PLA) allows the detection and subcellular localization of protein-protein interactions with high specificity. We recently developed a high-content screening model based on primary hippocampal neurons cultured in 384-well plates and screened a library of ∼1100 compounds
R J Wechsler-Reya et al.
Molecular and cellular biology, 18(1), 566-575 (1998-01-07)
Bin1 is a Myc-interacting protein with features of a tumor suppressor. The high level of Bin1 expression in skeletal muscle prompted us to investigate its role in muscle differentiation. Significant levels of Bin1 were observed in undifferentiated C2C12 myoblasts, a
Stephanie L Adams et al.
Journal of neuropathology and experimental neurology, 75(8), 779-790 (2016-10-22)
Genome-wide association studies have established BIN1 (Bridging Integrator 1) as the most significant late-onset Alzheimer disease (AD) susceptibility locus after APOE We analyzed BIN1 protein expression using automated immunohistochemistry on the hippocampal CA1 region in 19 patients with either no
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