L8912

L-Leucine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

• 동의어(들): (S)-Leucine, (S)-2-Amino-4-methylpentanoic acid
• Linear Formula: (CH₃)₂CHCH₂CH(NH₂)CO₂H
• CAS Number: 61-90-5
• Molecular Weight: 131.17
• Beilstein: 1721722
• EC Number: 200-522-0
• MDL number: MFCD00002617
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24896510
• NACRES: NA.26

속성

• product name: L-Leucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
• 생물학적 소스: non-animal source
• Quality Level: 300
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• 분석: 98.5-101.0%
• 형태: powder
• 광학 활성: [α]20/D 14.9 to 16.0°, c = 4 in 6 M HCl; [α]25/D 14.9 to 17.3 °, c = 4 in 6 M HCl
• 품질: meets EP, JP, USP testing specifications
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• 색상: white
• mp: >300 °C (lit.)
• solubility: 1 M HCl: 50 mg/mL
• 양이온 미량물: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: <0.02%; heavy metals: ≤10 ppm
• 응용 분야: peptide synthesis; pharmaceutical (small molecule)
• 작용기: amine; carboxylic acid
• 저장 온도: room temp
• SMILES string: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• InChI key: ROHFNLRQFUQHCH-YFKPBYRVSA-N

설명

일반 설명

Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.

애플리케이션

L-Leucine has been used:

• as a hypertrophic agent to monitor its effects on myotubes.
• as a component of PMG media for culturing yeast.
• in myotube protein synthesis analysis in skeletal muscle cells.
• to study its effects on hepatic lipid metabolism.

생화학적/생리학적 작용

Leucine plays a role in intracellular signaling, gene transcription, and translation. It promotes the synthesis of protein by activating the mammalian target of the rapamycin (mTOR) signaling pathway in placental cells, skeletal muscles, and adipose tissue. Leucine inhibits protein degradation and promotes mitochondrial biogenesis, glucose metabolism, and fatty acid oxidation to provide energy for protein synthesis.

기타 정보

For additional information on our range of Biochemicals, please complete this form.

The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)