07-276

Anti-PDGFRα Antibody

Upstate^®, from rabbit

• 동의어(들): Anti-Anti-CD140A, Anti-Anti-PDGFR-2, Anti-Anti-PDGFR2
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse
• 포장: antibody small pack of 25 μL
• 제조업체/상표: Upstate^®
• 기술: immunoprecipitation (IP): suitable; western blot: suitable
• 동형: IgG
• NCBI 수납 번호: NM_011058
• UniProt 수납 번호: P16234
• 배송 상태: ambient
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PDGFRA(5156)

설명

일반 설명

Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation, and also lead to activation of the Ras, Raf and ERK 1 and 2 pathway.

특이성

Recognizes PDGF Receptor alpha.

면역원

peptide corresponding to amino acids 1035-1053 (C-GKRNRHSSQTSEESAIETG) of human PDGF Receptor α

애플리케이션

Detect PDGFRα using this Anti-PDGFRα Antibody validated for use in IP & WB.

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

품질

routinely evaluated by immunoblot on 3T3/NIH cell lysate

표적 설명

150/170 kDa (doublet)

물리적 형태

ImmunoAffinity Purified

Protein A Purified immunoglobulin in 0.14 M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

분석 메모

Control
HeLa cells, extracts from 3T3/NIH or HepG2 cells, human brain tissue

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.