14-440-M

PKA Protein, Recombinant, 10 µg

Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.

• UNSPSC 코드: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

속성

• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in E. coli; expressed in BL21 DE3 cells
• 제품 라인: Upstate^®
• 양식: liquid
• 특이 활성도: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.); 8580 U/mg
• 유통기한: 1 yr
• 분자량: M_w 40.7 kDa
• 정제법: chromatography
• 종 반응성: human
• 제조업체/상표: Upstate^®
• 기술: activity assay: suitable (kinase)
• solubility: water: soluble
• 수납 번호(accession number): (FUNCTION: SwissProt: P17612 # Phosphorylates a large number of substrates in the cytoplasm and the nucleus. ); NM_002730.3
• NCBI 수납 번호: NM_002730.3; NM_207518.1
• UniProt 수납 번호: P17612
• 저장 온도: −70°C
• 유전자 정보: human ... PRKACA(46909581)

설명

일반 설명

Research area: Cell Signaling

Product Source: Expressed in E.coli BL21 (DE3) pLysS cells Recombinant human full length PKA, catalytic subunit type alpha, untagged Protein kinase A (PKA) is a serine protein kinase and heterotetrameric holoenzyme that targets serine and threonine residues.

Recombinant human full length PKA, catalytic subunit type alpha, untagged

생화학적/생리학적 작용

Protein Target: PKA; Target Sub-Family: AGC. Protein kinases are vital for integrating signaling networks within eukaryotic cells. In Hedgehog-responsive cells, PKA is crucial for regulating proliferation and fate determination by influencing Hedgehog signaling transduction. PKA has numerous targets that are linked to adhesion or migration.

포장

Also available in 10 μg size and in bulk

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-440M when ordering the 250 µg size.

품질

routinely evaluated by phosphorylation of Kemptide substrate in vitro

표적 설명

PKA

결합

Replaces: 14-114

물리적 형태

Phosphocellulose P11 chromatography

저장 및 안정성

1 year at -70°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1