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Merck
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주요 문서

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361550

Sigma-Aldrich

BIO

≥97% (HPLC), solid, GSK-3GSK-3α/β inhibitor, Calbiochem

동의어(들):

GSK-3 Inhibitor IX, BIO, (2ʹ Z,3ʹ E)-6-Bromoindirubin-3ʹ-oxime, BIO, (2ʹZ,3ʹE)-6-Bromoindirubin-3ʹ-oxime

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About This Item

실험식(Hill 표기법):
C16H10BrN3O2
CAS Number:
667463-62-9
Molecular Weight:
356.17
MDL number:
MFCD08705318
UNSPSC 코드:
12352200
NACRES:
NA.77

제품명

GSK-3 Inhibitor IX, BIO, CAS 667463-62-9, is a cell-permeable, highly potent, selective, reversible, and ATP-competitive inhibitor of GSK-3α/β (IC₅₀ = 5 nM). Maintains self-renewal in human & mouse embryonic stem cells.

Quality Level

100

분석

≥97% (HPLC)

양식

solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
protect from light

색상

purple

solubility

DMSO: 5 mg/mL

배송 상태

wet ice

저장 온도

2-8°C

SMILES string

Brc1cc2c(cc1)\C(=C3\Nc4c(cccc4)C\3N=O)\C(=O)N2

InChI

1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,14,18H,(H,19,21)/b15-13-

InChI key

WFRDXNRAUPBBTO-SQFISAMPSA-N

생화학적/생리학적 작용

Cell permeable: yes
Product competes with ATP.
Reversible: yes

포장

Packaged under inert gas

경고

Toxicity: Carcinogenic / Teratogenic (D)

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

시험 성적서(COA)

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