444218

MMP-3 Inhibitor I

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 동의어(들): MMP-3 Inhibitor I, Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor
• 실험식(Hill 표기법): C₂₇H₄₆N₁₀O₉S
• Molecular Weight: 686.78
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• 색상: white
• solubility: water: 1 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Inhibits matrix metalloproteinase-3 (stromelysin) (IC₅₀ = 5 µM). The inhibitor is based on a segment from the conserved region of the NH₂-terminal propeptide domain.

Inhibits the matrix metalloproteinase MMP-3 (IC₅₀ = 5 µM).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
MMP-3

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 5 µM against MMP-3

경고

Toxicity: Standard Handling (A)

서열

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂

물리적 형태

Supplied as a trifluroacetate salt.

재구성

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.

기타 정보

Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable