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Merck
모든 사진(1)

주요 문서

481907

Millipore

Nicotinamide

Precursor of the coenzymes NAD+ and NADP+.

동의어(들):

Nicotinamide, Niacinamide, Nicotinic Acid Amide

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About This Item

실험식(Hill 표기법):
C6H6N2O
CAS Number:
Molecular Weight:
122.12
MDL number:
UNSPSC 코드:
41116107
NACRES:
NA.25

Quality Level

분석

≥99% (HPLC)

양식

solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
protect from light

불순물

≤0.2% Nicotinic acid (TLC)

색상

white

solubility

water: soluble

양이온 미량물

heavy metals (as Pb): ≤0.003%

배송 상태

ambient

저장 온도

15-25°C

SMILES string

NC(=O)c1cnccc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

일반 설명

Precursor of the coenzymes NAD+ and NADP+.

경고

Toxicity: Irritant (B)

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

302.0 °F - closed cup

Flash Point (°C)

150 °C - closed cup


시험 성적서(COA)

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문서 라이브러리 방문

Ok-Seon Kwon et al.
Cancers, 12(4) (2020-04-12)
The role of Situin 1 (SIRT1) in tumorigenesis is still controversial due to its wide range of substrates, including both oncoproteins and tumor suppressors. A recent study has demonstrated that SIRT1 interferes in the Kirsten rat sarcoma viral oncogene homolog
Xing Jian et al.
Nature communications, 12(1), 4338-4338 (2021-07-17)
Previous GWAS studies identified non-coding loci with parent-of-origin-specific effects on Type 2 diabetes susceptibility. Here we report the molecular basis for one such locus near the KRTAP5-6 gene on chromosome 11. We determine the pattern of long-range contacts between an enhancer
Laszlo A Groh et al.
Immunometabolism, 3(3), e210025-e210025 (2021-07-17)
Following brief exposure to endogenous atherogenic particles, such as oxidized low-density lipoprotein (oxLDL), monocytes/macrophages can adopt a long-term pro-inflammatory phenotype, which is called trained immunity. This mechanism might contribute to the chronic low-grade inflammation that characterizes atherosclerosis. In this study
Ildem Akerman et al.
Cell reports, 35(2), 108981-108981 (2021-04-15)
Despite the central role of chromosomal context in gene transcription, human noncoding DNA variants are generally studied outside of their genomic location. This limits our understanding of disease-causing regulatory variants. INS promoter mutations cause recessive neonatal diabetes. We show that
Ming Hu et al.
Cell reports, 34(5), 108703-108703 (2021-02-04)
Using chromatin conformation capture, we show that an enhancer cluster in the STARD10 type 2 diabetes (T2D) locus forms a defined 3-dimensional (3D) chromatin domain. A 4.1-kb region within this locus, carrying 5 T2D-associated variants, physically interacts with CTCF-binding regions

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