8.20128

Saccharin

for synthesis

• 동의어(들): Saccharin
• 실험식(Hill 표기법): C₇H₅NO₃S
• CAS Number: 81-07-2
• Molecular Weight: 183.18
• MDL number: MFCD00005866
• UNSPSC 코드: 12352115
• EC 인덱스 번호: 201-321-0
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: ≥98.0% (acidimetric)
• 형태: crystals
• mp: 228-230 °C
• 저장 온도: 2-30°C
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• InChI key: CVHZOJJKTDOEJC-UHFFFAOYSA-N

설명

애플리케이션

• Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).


• Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).

분석 메모

Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable