8.52032

Fmoc-His(Trt)-OH

Novabiochem^®

• 동의어(들): Fmoc-His(Trt)-OH, N-α-Fmoc-N-im-trityl-L-histidine
• 실험식(Hill 표기법): C₄₀H₃₃N₃O₄
• CAS Number: 109425-51-6
• Molecular Weight: 619.71
• MDL number: MFCD00043332
• UNSPSC 코드: 12352209
• NACRES: NA.22

속성

• Quality Level: 400
• 제품 라인: Novabiochem^®
• 분석: ≥97.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• 양식: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• 제조업체/상표: Novabiochem^®
• mp: 130-145 °C (decomposition)
• 응용 분야: peptide synthesis
• 작용기: Fmoc
• 저장 온도: −20°C (−15°C to −25°C)
• SMILES string: [n]4(cnc(c4)C[C@H](NC(=O)OCC5c6c(cccc6)c7c5cccc7)C(=O)O)C(c3ccccc3)(c2ccccc2)c1ccccc1
• InChI: 1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1
• InChI key: XXMYDXUIZKNHDT-QNGWXLTQSA-N

설명

일반 설명

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of histidine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.

결합

Replaces: 04-12-1065

분석 메모

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 160 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His(Trt)-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable