AB10439

Anti-PACSIN1 Antibody, NT

from rabbit

• 동의어(들): protein kinase C and casein kinase substrate in neurons 1, syndapin I
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 클론: polyclonal
• application: IHC; WB
• 종 반응성: human, mouse
• 기술: immunohistochemistry: suitable (paraffin); western blot: suitable
• citations: 1

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human, mouse
• 기술: immunohistochemistry: suitable (paraffin); western blot: suitable
• UniProt 수납 번호: Q9BY11
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PACSIN1(29993)

설명

일반 설명

PACSINs, also known as syndapins, are a protein family consisting of three members that have been implicated in synaptic vesicular membrane trafficking and regulation of dynamin-mediated endocytotic processes (Cuajungco, 2006). It is presumed that all isoforms bind Dynamin, Synaptojanin 1 and N-WASP through their Src homology 3 domains. While PACSIN1 appears to be restricted to neural tissues, two PACSINs are more widespread with PACSIN2 being ubiquitously expressed and PACSIN3 present mainly in skeletal muscle, heart and lung (Modregger, 2001). PACSIN1 has been implicated as playing a central role in synaptic vesicle recycling (Kessels, 2004). Expected molecular weight is 51 kDa.

특이성

Reactivity with other species has not been tested.

The antibody recognizes human PACSIN1.

면역원

KLH conjugated synthetic peptide selected from the N-terminal region of human PACSIN1.

애플리케이션

Anti-PACSIN1 Antibody, N-terminus detects level of PACSIN1 & has been published & validated for use in WB, IH(P).

품질

Evaluated on a representative lot by Western blot on mouse brain lysate using a 1:100 - 1:500 dilution of Anti-PACSIN1.

표적 설명

~57 kDa

물리적 형태

Format: Purified

PBS containing 0.09% NaN3.

저장 및 안정성

Maintain at 2-8ºC for up to 6 months from date of receipt. -20ºC is recommended for long term storage.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable