추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
secondary antibodies
클론
HP6001, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
ELISA: suitable
radioimmunoassay: suitable
western blot: suitable
동형
IgG2b
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... FCGR2B(2213)
특이성
Human IgG1 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 100% human IgG subclass 2- 0.25% human IgG subclass 3- 0.01%
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
human IgG subclass 4-0.01% Isoelectric Focusing: mean pI 8.0
면역원
Epitope: Fc fragment
애플리케이션
Detect Human IgG1 using this Mouse anti-Human IgG1 Antibody, clone HP6001, Fc validated for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG1 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
결합
Replaces: MABN1055
물리적 형태
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl containing 0.1% sodium azide.
저장 및 안정성
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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Clinical cancer research : an official journal of the American Association for Cancer Research, 28(1), 201-214 (2021-10-15)
mAbs blocking immune checkpoints have emerged as important cancer therapeutics, as exemplified by systemic administration of the IgG1 anti-CD47 mAb that blocks the "don't eat me" pathway. However, this strategy is associated with severe toxicity. To improve therapeutic efficacy while
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Tian, et al.
Nature cancer, 3, 1318-1335 (2023)
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Nature communications, 12(1), 5908-5908 (2021-10-10)
Oncolytic herpes simplex virus-1 is capable of lysing tumor cells while alerting the immune system. CD47, in collaboration with SIRPα, represents an important immune checkpoint to inhibit phagocytosis by innate immune cells. Here we show locoregional control of glioblastoma by
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R C Williams et al.
Arthritis and rheumatism, 40(1), 109-123 (1997-01-01)
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