MAB3224

Anti-Basal Cell Cytokeratin Antibody

Chemicon^®, from mouse

• 동의어(들): Cytokeratin 5 and others
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 종 반응성: rat, quail, guinea pig, human, hamster, canine, rabbit, pig, chicken
• 제조업체/상표: Chemicon^®
• 기술: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• 동형: IgG1
• NCBI 수납 번호: NM_000424.3
• UniProt 수납 번호: P13647
• 배송 상태: dry ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... KRT5(3852)

설명

일반 설명

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies.

특이성

MAB3224 is a broadly reacting cytokeratin antibody which reacts with cytokeratin 5 among others. It stains basal cells in combined and stratified epithelial tissues. It recognizes the stem cell population, including the so-called amplifying cell in the prostate epithelium.

면역원

Human cytokeratins.

애플리케이션

Anti-Basal Cell Cytokeratin Antibody detects level of Basal Cell Cytokeratin & has been published & validated for use in FC, IC, IH & WB.

Research Category
Cell Structure

Research Sub Category
Cytokeratins

Western blot: 1:100-1:1,000
Immunohistochemistry on frozen tissue sections: 1:100-1:200
Immunocytochemistry: 1:100-1:200
Flow cytometry: 1:100-1:200
Optimal working dilutions must be determined by the end user.

물리적 형태

Format: Purified

Purified immunoglobulin. Purified immunoglobulin in buffer with 0.1% sodium azide.

저장 및 안정성

Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable