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Merck
모든 사진(1)

문서

ACOA-RO

Roche

Acetyl-Coenzyme A

85% (Enzymatic and Absorbance), 2% (lithium)

동의어(들):

Acetyl-Coenzyme A, acetyl-coa

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About This Item

UNSPSC 코드:
12352204

설명

Chemical Formula: C23H35N7O17P3SLi3

Quality Level

분석

85% (Enzymatic and Absorbance)

형태

solid

분자량

Mr 809.6 (acetyl-CoA)
Mr 827.4 (acetyl-CoA-Li3)

포장

pkg of 010 mg (10101893001)
pkg of 200 mg (11585371001)
pkg of 050 mg (10101907001)

제조업체/상표

Roche

농도

2% (lithium)

저장 온도

2-8°C

일반 설명

Acetyl-Coenzyme A, trilithium salt

애플리케이션

Acetyl-Coenzyme A is used to assay CAT enzyme activity in cell extracts using radioisotopes. CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetylcoenzyme A to chloramphenicol. A number of assays have been developed to measure CAT activity in cell extracts. Acetyl-Coenzyme A has also been used to determine citrate synthase activity.

생화학적/생리학적 작용

Acetyl-Coenzyme A (Ac-CoA) is the end product of glycolysis and takes part in the Ac-CoA pathway, which is a metabolic pathway for carbon compounds. Ac-CoA is important in cholesterol synthesis. It also takes part in fatty acid biosynthesis and catabolism of polyamines like spermine and spermidine. A low level of Ac-CoA leads to a loss in glial cell and neuronal function. Ketone bodies and triglycerides give rise to Ac-CoA on hydrolysis and this indirectly leads to increased histone acetylation.

제조 메모

Working solution: Optimal solvent: water or aqueous solution with a weak acidic pH (4 to 5).
Storage conditions (working solution): -15 to -25 °C
50 mg/ml in phosphate buffer, pH 7, is stable for 3 weeks at -15 to -25 °C. Unfrozen solutions should be immediately used.

기타 정보

For life science research only. Not for use in diagnostic procedures.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Biochemistry null
Giosalba Burgio et al.
Biochimica et biophysica acta, 1799(10-12), 671-680 (2010-05-25)
The eukaryotic genome is a highly organized nucleoprotein structure comprising of DNA, histones, non-histone proteins, and RNAs, referred to as chromatin. The chromatin exists as a dynamic entity, shuttling between the open and closed forms at specific nuclear regions and
Jean-Pierre Montmayeur and Johannes le Coutre
Fat Detection-Taste, Texture, and Post Ingestive Effects null
Morten Scheibye-Knudsen et al.
Cell metabolism, 20(5), 840-855 (2014-12-03)
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in genes encoding the DNA repair proteins CS group A or B (CSA or CSB). Since dietary interventions can alter neurodegenerative processes, Csb(m/m) mice were
Agnieszka Jankowska-Kulawy et al.
Neurochemistry international, 57(7), 851-856 (2010-09-21)
Several pathologic conditions are known to cause thiamine deficiency, which induce energy shortages in all tissues, due to impairment of pyruvate decarboxylation. Brain is particularly susceptible to these conditions due to its high rate of glucose to pyruvate-driven energy metabolism.

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