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Merck
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주요 문서

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34044

Supelco

Tiamulin

VETRANAL®, analytical standard

동의어(들):

(1S,2R,3S,4S,6R,7S,14R)-6-[(2-Diethylaminoethylthio)acetoxy]-3-hydroxy-2,4,7,14-tetramethyl-4-vinyltricyclo[5,4,3,01.8]tetradecan-9-one

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C28H47NO4S
CAS Number:
55297-95-5
Molecular Weight:
493.74
EC Number:
259-580-0
UNSPSC 코드:
41116107
PubChem Substance ID:
24860813
NACRES:
NA.24

Grade

analytical standard

Quality Level

100

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

동작 모드

enzyme | inhibits

저장 온도

2-8°C

SMILES string

CCN(CC)CCSCC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@H](C)[C@@]23CC[C@@H](C)C1(C)[C@@H]2C(=O)CC3

InChI

1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1

InChI key

UURAUHCOJAIIRQ-QGLSALSOSA-N

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일반 설명

Chemical structure: macrolide
Tiamulinis a veterinary drug with very low water solubility (0.000524 mg/mL). Its mode of action involves suppressing protein synthesis in bacteria.

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
For detailed application information, please see the Frequently Asked Questions (FAQ) section at the bottom of this page.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

유해 및 위험 성명서

H413

예방조치 성명서

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
BCCM4270
BCCL6936
BCCH0386
BCCC8469
BCBZ9202

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

"Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin?
Schlunzen F, et al.
Molecular Microbiology, 54(05), 1287-1294 (2004)
Petra Reinhold et al.
Veterinary journal (London, England : 1997), 187(3), 405-407 (2010-08-31)
The effect of short-term antimicrobial treatment on natural excretion of Chlamydia suis in rectal swabs and C. suis and Chlamydophila psittaci in nasal swabs was investigated in 47 clinically normal piglets by quantitative real-time PCR. Pigs were treated IM with
Harold M J F van der Heijden et al.
Tijdschrift voor diergeneeskunde, 136(6), 410-416 (2011-06-28)
Histomonosis, a parasitic disease of galliformes and sporadically of other birds caused by Histomonas meleagridis, can result in very high mortality, especially in turkeys. The ban on the last antihistomonal drug prompted an urgent search for alternative prevention and treatment
Andrew Pridmore et al.
Veterinary microbiology, 151(3-4), 409-412 (2011-04-19)
Tiamulin activity was measured against 19 UK field isolates of Actinobacillus pleuropneumoniae collected between 2003 and 2009 and the type strain ATCC 27090 as a control, with the intention of comparing broth with serum as growth media. Broth microdilution MIC/MBC
R Hauck et al.
Avian diseases, 54(2), 936-938 (2010-07-09)
In this study, we investigated the activity of tiamulin fumerate against three strains of Histomonas meleagridis in vitro under different conditions. Tiamulin reduced histomonal growth of all three strains at concentrations of 20 ppm and higher. Cultures in phosphate-buffered saline-based
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