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Merck
모든 사진(1)

문서

33864

Supelco

Tilmicosin

VETRANAL®, analytical standard, mix of isomers

동의어(들):

20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin

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About This Item

실험식(Hill 표기법):
C46H80N2O13
Molecular Weight:
869.13
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

CC1OC(OCC(C(CC)O2)/C=C(/C=C/C(C(C)CC(CCN3CC(C)CC(C)C3)C(OC4OC(C)C(O)C(N(C)C)C4O)C(C)C(O)CC2=O)=O)C)C(OC)C(OC)C1O

InChI

1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

InChI key

JTSDBFGMPLKDCD-XVFHVFLVSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Tilmicosin is a semisynthetic macrolide antibiotic, with broad spectrum activity towards Mycoplasma spp., Pasteurella spp., and various gram-positive organisms in animals.

애플리케이션

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tilmicosin may be used as a reference standard for the determination of the analyte in chicken, swine, cattle, sheep tissues and milk samples using liquid chromatography with ultraviolet detection (LC-UV).

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazardExclamation markEnvironment

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

표적 기관

Cardio-vascular system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

Jacob Poehlsgaard et al.
ACS chemical biology, 7(8), 1351-1355 (2012-05-09)
The veterinary antibiotic tildipirosin (20,23-dipiperidinyl-mycaminosyl-tylonolide, Zuprevo) was developed recently to treat bovine and swine respiratory tract infections caused by bacterial pathogens such as Pasteurella multocida. Tildipirosin is a derivative of the naturally occurring compound tylosin. Here, we define drug-target interactions
Niels Møller Andersen et al.
Antimicrobial agents and chemotherapy, 56(11), 6033-6036 (2012-08-29)
Tildipirosin is a 16-membered-ring macrolide developed to treat bacterial pathogens, including Mannheimia haemolytica and Pasteurella multocida, that cause respiratory tract infections in cattle and swine. Here we evaluated the efficacy of tildipirosin at inhibiting protein synthesis on the ribosome (50%
Yingyu Liu et al.
Microbial drug resistance (Larchmont, N.Y.), 18(6), 604-615 (2012-09-01)
The Haemophilus parasuis respiratory tract pathogen poses a severe threat to the swine industry despite available antimicrobial therapies. To gain a more detailed understanding of the molecular mechanisms underlying H. parasuis response to tilmicosin treatment, microarray technology was applied to
Shuyu Xie et al.
Particle and fibre toxicology, 8, 33-33 (2011-11-22)
Our previous studies demonstrated that tilmicosin-loaded hydrogenated castor oil solid lipid nanoparticles (Til-HCO-SLN) are a promising formulation for enhanced pharmacological activity and therapeutic efficacy in veterinary use. The purpose of this work was to evaluate the acute toxicity of Til-HCO-SLN.
Determination of tilmicosin residues in cow and sheep milk by liquid chromatography.
Stobba-Wiley.MC and Readnour.SR
Journal of AOAC (Association of Official Analytical Chemists) International, 83(3), 555-562 (2000)

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