추천 제품
Grade
analytical standard
Quality Level
분석
≥99.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable
응용 분야
cleaning products
cosmetics
food and beverages
personal care
형식
neat
저장 온도
2-8°C
SMILES string
O=NN1CCCC1c2cccnc2
InChI
1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2
InChI key
XKABJYQDMJTNGQ-UHFFFAOYSA-N
일반 설명
N′-Nitrosonornicotine is a tobacco specific nitrosamine, which is found to be carcinogenic in nature. It is produced via nitrosation of nicotine during the process of curing, aging, processing and smoking of tobacco.
애플리케이션
N′-Nitrosonornicotine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes
Patten JC, et al.
Carcinogenesis, 18(8), 1623-1630 (1997)
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Molecular ecology resources, 17(6), e46-e62 (2017-05-11)
Reliable information on past and present vegetation is important to project future changes, especially for rapidly transitioning areas such as the boreal treeline. To study past vegetation, pollen analysis is common, while current vegetation is usually assessed by field surveys.
Comparative carcinogenicity in A/J mice and metabolism by cultured mouse peripheral lung of N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and their analogues
Castonguay A, et al.
Cancer Research, 43(3), 1223-1229 (1983)
Marc Besson et al.
PloS one, 12(6), e0178795-e0178795 (2017-06-09)
For marine fishes with a bipartite life cycle, pelagic larval dispersal can shape the distribution, connectivity, composition and resilience of adult populations. Numerous studies of larval dispersal, and associated settlement and recruitment processes, have examined the relationship between population connectivity
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