추천 제품
Grade
analytical standard
Quality Level
분석
≥97.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable
응용 분야
cleaning products
cosmetics
food and beverages
personal care
형식
neat
저장 온도
2-8°C
SMILES string
O=NN1CC=CCC1c2cccnc2
InChI
1S/C10H11N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h1-4,6,8,10H,5,7H2
InChI key
ZJOFAFWTOKDIFH-UHFFFAOYSA-N
일반 설명
Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706031. N-Nitrosoanatabine (NAT), classified in the third group of carcinogens, belongs to the class of tobacco-specific nitrosamines (TSNAs). TSNAs are carcinogenic compounds, formed through the burning, curing and fermentation of tobacco leaves. Their levels in tobacco can vary and significantly correlate to the amount of nitrate in tobacco. NAT is produced together with N′-nitrosonornicotine [NNN] and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [NNK]) in tobacco. It can be detected in E-cigarette cartridges, mainstream tobacco smoke, snuff, etc.
애플리케이션
N-Nitrosoanatabine has been used as an analytical reference standard for the quantification of the analyte in urine samples using SupelMIP solid phase extraction (SPE) followed by liquid chromatography coupled to mass spectrometry (LC-MS). It may also be used as an analytical reference standard for the quantification of the analyte in human urine samples, replacement liquids of electronic cigarettes, snuff samples using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
N-Nitroso compounds in cigarette tobacco and their occurrence in mainstream tobacco smoke
Carcinogenesis, 12(2), 257-261 (1991)
Tobacco Control, An Issue of Nursing Clinics-E-Book, 47(1) (2012)
Drug testing and analysis, 8(10), 1095-1099 (2015-12-02)
Approximately 600 million people worldwide practise the carcinogenic habit of betel nut/quid chewing. Carcinogenic N-nitroso compounds have been identified in saliva or urine of betel chewers and the betel alkaloid arecoline in hair from habitual betel quid chewers. However, the
Analytical method for measurement of tobacco-specific nitrosamines in E-cigarette liquid and aerosol
Applied Sciences, 8(12), 2699-2699 (2018)
Analysis of tobacco-specific N-nitrosamines in snuff by ethyl acetate extraction and liquid chromatography-tandem mass spectrometry
Journal of Chromatography A, 1008(2), 135-143 (2003)
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