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Merck
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Key Documents

A42409

Sigma-Aldrich

2-Aminobiphenyl

≥96.5% purity, powder or crystals

동의어(들):

2-Biphenylylamine, 2-Phenylaniline

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About This Item

Linear Formula:
C6H5C6H4NH2
CAS Number:
Molecular Weight:
169.22
Beilstein:
471874
EC Number:
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

2-Aminobiphenyl, ≥96.5% (GC)

vapor density

5.8 (vs air)

Quality Level

분석

≥96.5% (GC)

형태

powder or crystals

autoignition temp.

842 °F

불순물

<0.1% 4-aminobiphenyl

색상

brown
off-white to yellow

bp

299 °C (lit.)

mp

47-50 °C (lit.)

solubility

water: insoluble

density

1.16 g/cm3 at 21 °C

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

Nc1ccccc1-c2ccccc2

InChI

1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2

InChI key

TWBPWBPGNQWFSJ-UHFFFAOYSA-N

유전자 정보

human ... UGT1A4(54657)

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일반 설명

2-Aminobiphenyl is a substrate for UGTs (UDP-glucuronosyltransferases), including UGT1A4, UGT2B13 and UGT2B16.

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

307.4 °F - closed cup

Flash Point (°C)

153 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
R Harzmann et al.
Urologia internationalis, 35(5), 340-350 (1980-01-01)
It takes 24 months to induce preinvasive carcinomas in the urinary bladder of dogs as reported in the literature. The transplantation of chemically induced carcinomas has never been successful. Therefore, it was looked for methods which enable a shortening of
Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Uesawa Y, et al.
Drug Metabolism and Disposition, 32, 1476-1481 (2004)
M M Marques et al.
Chemical research in toxicology, 3(6), 559-565 (1990-11-01)
The complementary pentadecamers d(5'-TACTCTTCTTGACCT) (strand A) and d(5'-AGGTCAAGAAGAGTA) (strand B), which span a portion of the mouse c-Ha-ras protooncogene centered around codon 61, were synthesized by using standard beta-cyanoethyl phosphoramidite chemistry and characterized by sequence analysis. Strand A, containing a

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