ALD00604

(+)-PSI Reagent

95%

• 동의어(들): (+)-Ψ, (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, Phosphorus-Sulfur Incorporation Reagent
• 실험식(Hill 표기법): C₁₆H₁₆F₅OPS₃
• CAS Number: 2245335-71-9
• Molecular Weight: 446.46
• UNSPSC 코드: 12352101
• NACRES: NA.22

속성

• 분석: 95%
• 형태: powder or crystals
• mp: 102-107 °C

설명

애플리케이션

Air- and moisture-tolerant, this (+)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat# ALD00602).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).

Learn more about PI and PSI reagents

기타 정보

Unlocking P(V): Reagents for chiral phosphorothioate synthesis

PSI on OpenFlask

법적 정보

PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable