I0599990
Isoprenaline hydrochloride
European Pharmacopoeia (EP) Reference Standard
동의어(들):
Isoprenaline hydrochloride, (±)-Isoproterenol hydrochloride, 1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride, N-Isopropyl-DL-noradrenaline hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H17NO3 · HCl
CAS Number:
Molecular Weight:
247.72
Beilstein:
3917363
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
pharmaceutical primary standard
API family
isoprenaline
제조업체/상표
EDQM
mp
165-175 °C (dec.) (lit.)
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-8°C
SMILES string
Cl.CC(C)NCC(O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key
IROWCYIEJAOFOW-UHFFFAOYSA-N
유전자 정보
human ... ADRB1(153) , ADRB2(154) , ADRB3(155)
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일반 설명
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
애플리케이션
Isoprenaline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
생화학적/생리학적 작용
β-adrenoceptor agonist; increases cytosolic cAMP.
포장
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
기타 정보
Sales restrictions may apply.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Christiane Neuber et al.
The Journal of pharmacology and experimental therapeutics, 349(1), 39-46 (2014-01-17)
Stimulation of myocardial β(1)-adrenoceptors (AR) is a major mechanism that increases cardiac function. We investigated the functional consequences of genetic β(1)-AR knockdown in three-dimensional engineered heart tissue (EHT). For β(1)-AR knockdown, short interfering RNA (siRNA) sequences targeting specifically the β(1)-AR
T S Higa et al.
Life sciences, 103(1), 41-48 (2014-03-19)
This study sought to determine the role of white adipose tissue (WAT) metabolism in the prevention of insulin resistance (IR) by physical training (PT). Male C57BL/6J mice were assigned into groups CHOW-SED (chow diet, sedentary; n=15), CHOW-TR (chow diet, trained;
Rishi K Somvanshi et al.
Biochimica et biophysica acta, 1843(4), 735-745 (2014-01-15)
In the present study, we report that somatostatin receptor 2 (SSTR2) plays a crucial role in modulation of β1AR and β2AR mediated signaling pathways that are associated with increased intracellular Ca(2+) and cardiac complications. In H9c2 cells, SSTR2 colocalizes with
Han-Jun Wang et al.
Hypertension (Dallas, Tex. : 1979), 64(4), 745-755 (2014-07-02)
The enhanced cardiac sympathetic afferent reflex (CSAR) contributes to the exaggerated sympathoexcitation in chronic heart failure (CHF). Increased sympathoexcitation is positively related to mortality in patients with CHF. However, the potential beneficial effects of chronic CSAR deletion on cardiac and
Peter Kubuš et al.
Circulation. Arrhythmia and electrophysiology, 7(2), 218-223 (2014-02-04)
Data on the results and clinical effect of an invasive risk stratification strategy in asymptomatic young patients with the Wolff-Parkinson-White electrocardiographic pattern are scarce. Eighty-five consecutive patients aged<18 years with a Wolff-Parkinson-White pattern and persistent preexcitation at maximum exercise undergoing
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