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Merck
모든 사진(3)

주요 문서

M6880

Sigma-Aldrich

Malachite Green oxalate salt

Powder, crystals or chunks

동의어(들):

N,N,N′,N′-Tetramethyl-4,4′-diaminotriphenylcarbenium oxalate, Basic Green 4

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About This Item

실험식(Hill 표기법):
C23H25N2 · C2HO4 · 0.5C2H2O4
CAS Number:
Molecular Weight:
463.50
색상 지수 번호:
42000
Beilstein:
3644550
EC Number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

제품명

Malachite Green oxalate salt, Technical grade

Grade

technical grade

Quality Level

양식

powder, crystals or chunks

기술

microbe id | staining: suitable

색상

metallic green

solubility

water: 1 mg/mL

λmax

616-620 nm in water

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

C[N+](C)=C1C=CC(C=C1)=C(C2=CC=C(N(C)C)C=C2)C3=CC=CC=C3.[O-]C(C(O)=O)=O

InChI

1S/C23H25N2.C2H2O4/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4;3-1(4)2(5)6/h5-17H,1-4H3;(H,3,4)(H,5,6)/q+1;/p-1

InChI key

REZFCYOVFCJTDG-UHFFFAOYSA-M

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일반 설명

The release of phosphate or pyrophosphate in an enzymatic reaction can be detected by malachite green and is measured spectrometrically at 660nm.

애플리케이션

Malachite Green oxalate salt has been used in biliary phospholipid analysis.
Malachite Green oxalate salt has been used:
  • in the preparation of malachite green-ammonium molybdate reagent, as a stop solution for starch synthase activity assay
  • to terminate the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) inhibition assay using phosphatidylinositol (3,4,5) triphosphate (PI(3,4,5)P3) as substrate
  • to determine trypanothione synthetase activity to measure inorganic phosphate release from adenosine triphosphate (ATP) during catalysis

생화학적/생리학적 작용

Malachite green is used in the treatment of fungal and parasitic infections in fish.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile.
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Journal of Lipid Research, 46, 1732-1732 (2005)
Combinatorial Chemistry: From Theory to Application (2006)
Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi
Mesias AC, et al.
Free Radical Biology & Medicine, 130, 23-34 (2019)
Targeting PTEN using small molecule inhibitors
Mak LH and Woscholski R
Methods, 77, 63-68 (2015)
Andrea C Mesías et al.
Free radical biology & medicine, 130, 23-34 (2018-10-26)
Chagas cardiomyopathy, caused by Trypanosoma cruzi infection, continues to be a neglected illness, and has a major impact on global health. The parasite undergoes several stages of morphological and biochemical changes during its life cycle, and utilizes an elaborated antioxidant

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