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Merck
모든 사진(1)

문서

T6750

Sigma-Aldrich

Thioglycolic acid solution

~70 % (w/w) in H2O

동의어(들):

Mercaptoacetic acid

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About This Item

Linear Formula:
HSCH2COOH
CAS Number:
Molecular Weight:
92.12
Beilstein:
506166
EC Number:
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.21

Quality Level

농도

~70 % (w/w) in H2O

density

1.25 g/mL at 25 °C (lit.)

저장 온도

2-8°C

SMILES string

OC(=O)CS

InChI

1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)

InChI key

CWERGRDVMFNCDR-UHFFFAOYSA-N

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주의사항

At room temperature, concentrations over about 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acid or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

픽토그램

Skull and crossbonesCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

266.0 °F - closed cup

Flash Point (°C)

130 °C - closed cup

개인 보호 장비

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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문서 라이브러리 방문

Baofu Han et al.
Colloids and surfaces. B, Biointerfaces, 100, 209-214 (2012-07-07)
Fluorescent carbon dots (CDs) were solvothermaly synthesized in water-glycol medium by using glucose as carbon source and then modified with polyethyleneimine (PEI) for the first time to improve fluorescence quality. The as-prepared CDs were monodispersed sphere particles with a diameter
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to
Heike E Friedl et al.
Biomaterials, 34(32), 7811-7818 (2013-07-28)
It was the purpose of this study to design and evaluate a chitosan derivative as mucoadhesive excipient for vaginal drug delivery systems. The chemical modification of chitosan was achieved by conjugation of thioglycolic acid (TGA) resulting in 1594 μmol thiol
Gizem Ayna et al.
PloS one, 7(6), e40069-e40069 (2012-07-07)
Pathogen-activated and damage-associated molecular patterns activate the inflammasome in macrophages. We report that mouse macrophages release IL-1β while co-incubated with pro-B (Ba/F3) cells dying, as a result of IL-3 withdrawal, by apoptosis with autophagy, but not when they are co-incubated
Kerstin Gradauer et al.
International journal of nanomedicine, 7, 2523-2534 (2012-06-09)
To develop mucoadhesive liposomes by anchoring the polymer chitosan-thioglycolic acid (chitosan-TGA) to the liposomal surface to target intestinal mucosal membranes. Liposomes consisting of phosphatidylcholine (POPC) and a maleimide-functionalized lipid were incubated with chitosan-TGA, leading to the formation of a thioether

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