496189

Chloroform

biotech. grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• 동의어(들): Methylidyne trichloride, Trichloromethane
• 실험식(Hill 표기법): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein: 1731042
• MDL number: MFCD00000826
• UNSPSC 코드: 12191502
• PubChem Substance ID: 329757487
• NACRES: NA.04

속성

• Grade: biotech. grade
• Quality Level: 100
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• 분석: ≥99.8%
• 형태: liquid
• 포함: 0.5-1.0% ethanol as stabilizer
• 불순물: <0.01% water
• 증발 잔류물: <0.0003%
• 색상: APHA: ≤10
• refractive index: n20/D 1.445 (lit.)
• pH: 5.2-6.4
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• 양이온 미량물: Pb: ≤0.05 ppm
• SMILES string: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

설명

일반 설명

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect. It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Low water content, minimal residue and clean UV spectra are the special characteristics of this biotech grade solvent. It can be utilized for biotechnological processes like protein sequencing, peptide and oligonucleotide synthesis. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.

애플리케이션

Chloroform may be used in the following processes:

• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
• Preparing phospholipid solutions.
• As a solvent in the photolysis reaction of ruthenium complexes.
• Solvent for recrystallization.
• Reference compound to detect the presence of chloroform in Tobacco smokes.
• Extractant in solvent extraction process.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372
• 예방조치 성명서: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• 표적 기관: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash