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Merck
모든 사진(1)

주요 문서

01930

Sigma-Aldrich

Adenosine 5′-monophosphate disodium salt

≥99.0% (HPLC)

동의어(들):

5′-AMPdisodium salt,, Adenylic acid disodium salt, 5′-AMP-Na2

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About This Item

실험식(Hill 표기법):
C10H12N5Na2O7P
CAS Number:
Molecular Weight:
391.18
Beilstein:
3586732
EC Number:
MDL number:
UNSPSC 코드:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51

생물학적 소스

microbial (Candida utilis)
synthetic

Quality Level

분석

≥99.0% (HPLC)

형태

powder

광학 활성

[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)

불순물

≤26% water

SMILES string

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

QGXLVXZRPRRCRP-IDIVVRGQSA-L

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6) and 5′-nucleotidase (EC 3.1.3.5).
Adenosine 5′-monophosphate disodium salt has been used:

  • as a dissolved organic phosphorus (DOP) compound to study its rate of hydrolysis in Escherichia coli lysates
  • to induce calcium responses in Fura2-loaded osteoblast (C2-OB)
  • as a nucleotide metabolite in the medium for the isolation, culture, and identification of glioma stem cells (GSCs)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Xiaoyu Xu et al.
Cell death & disease, 12(3), 277-277 (2021-03-17)
Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment. However, the mechanism underlying the rewiring of their metabolism in low pH
Nicholas Mikolajewicz et al.
Biophysical journal, 116(10), 2009-2022 (2019-05-06)
The skeleton constantly interacts and adapts to the physical world. We have previously reported that physiologically relevant mechanical forces lead to small repairable membrane injuries in bone-forming osteoblasts, resulting in release of ATP and stimulation of purinergic (P2) calcium responses
Aric H Mine et al.
Frontiers in microbiology, 12, 641700-641700 (2021-04-27)
The availability of phosphorus limits primary production in large regions of the oceans, and marine microbes use a variety of strategies to overcome this limitation. One strategy is the production of alkaline phosphatase (APase), which allows hydrolysis of larger dissolved
5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes.
Tsuchiya Y, Denison FC, et al.
Bioscience Reports, 32(2), 197-213 (2011)
Jiahuan Liu et al.
Scientific reports, 10(1), 21811-21811 (2020-12-15)
The present study was conducted to estimate the effects of dietary carbohydrates on muscle quality and the underlying mechanisms. Six isonitrogenous and isolipidic diets were formulated to contain graded levels of carbohydrates (0%, 8%, 12%, 16%, 20% and 24%, respectively).

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