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Merck
모든 사진(1)

문서

30170

Sigma-Aldrich

L-Cysteic acid monohydrate

≥99.0% (T), suitable for LC/MS

동의어(들):

(R)-2-Amino-3-sulfopropionic acid

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About This Item

Linear Formula:
HO3SCH2CH(NH2)CO2H·H2O
CAS Number:
Molecular Weight:
187.17
Beilstein:
3714036
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

L-Cysteic acid monohydrate, ≥99.0% (T)

Quality Level

분석

≥99.0% (T)

형태

powder or crystals

광학 활성

[α]20/D +7.5±0.5°, c = 5% in H2O

기술

LC/MS: suitable

색상

white to faint yellow

mp

267 °C (dec.) (lit.)

solubility

H2O: soluble

응용 분야

peptide synthesis

SMILES string

[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1

InChI key

PCPIXZZGBZWHJO-DKWTVANSSA-N

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애플리케이션

Internal standard for amino acid analysis.

생화학적/생리학적 작용

L-Cysteic acid is a sulfur containing aspartate analogue that may be used as a competitive inhibitor of the bacterial aspartate:alanine antiporter (AspT) exchange of aspartate and in other aspartate biological systems. L-Cysteic acid is used in monomeric surfactant development.
L-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
A E Kingston et al.
Neuropharmacology, 37(3), 277-287 (1998-07-29)
Comparison of the pharmacological effects of a range of sulphur-containing amino acids on human mGluR1alpha and mGluR5a has been undertaken. cDNAs of each mGluR were transfected into a Syrian hamster tumour cell line AV12-664 that was previously transfected with the
Naoko Arashida et al.
Analytica chimica acta, 954, 77-87 (2017-01-14)
Amino acids and their related metabolites play important roles in various physiological processes and have consequently become biomarkers for diseases. However, accurate quantification methods have only been established for major compounds, such as amino acids and a limited number of

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