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Merck
모든 사진(1)

주요 문서

30800

Sigma-Aldrich

7-Dehydrocholesterol

≥95.0% (HPLC)

동의어(들):

(−)-7-Dehydrocholesterol, 3β-Hydroxy-5,7-cholestadiene, 5,7-Cholestadien-3β-ol, Provitamin D3

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About This Item

실험식(Hill 표기법):
C27H44O
CAS Number:
Molecular Weight:
384.64
Beilstein:
2224615
EC Number:
MDL number:
UNSPSC 코드:
12352211
eCl@ss:
39023139
PubChem Substance ID:
NACRES:
NA.79

생물학적 소스

synthetic

Quality Level

분석

≥95.0% (HPLC)

형태

powder or crystals

광학 활성

[α]20/D -115±8°, c = 1% in chloroform

색상

white to faint yellow

mp

148-152 °C (lit.)

저장 온도

−20°C

SMILES string

[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1

InChI key

UCTLRSWJYQTBFZ-DDPQNLDTSA-N

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일반 설명

7-Dehydrocholesterol (7-DHC), a 5,7-conjugated diene sterol is a biosynthetic precursor of cholesterol. It helps in the production of vitamin D3 when exposed to ultraviolet B (UVB) radiation.

애플리케이션

7-Dehydrocholesterol has been used as an internal standard to determine sterols.

생화학적/생리학적 작용

Down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Amaranth oil increased fecal excretion of bile acid but had no effect in reducing plasma cholesterol in hamsters
de Castro lIA, et al.
Lipids, 48, 609-618 (2013)
7-Dehydrocholesterol (7-DHC), But Not Cholesterol, Causes Suppression of Canonical TGF-beta Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD)
Huang SS, et al.
Journal of Cellular Biochemistry, 118(6), 1387-1387 (2017)
Nicholas A Robinson et al.
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American journal of medical genetics. Part A, 173(8), 2246-2250 (2017-06-03)
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Vitamin D, Calcium, and the Epidermis
Vitamin D, 1, 527-544 (2018)

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