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Merck
모든 사진(3)

문서

L5768

Sigma-Aldrich

Lanosterol

≥93%, powder

동의어(들):

3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol

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모든 사진(3)

About This Item

실험식(Hill 표기법):
C30H50O
CAS Number:
79-63-0
Molecular Weight:
426.72
EC Number:
201-214-9
MDL number:
MFCD00021108
UNSPSC 코드:
12352211
PubChem Substance ID:
24896417
NACRES:
NA.77

분석

≥93%

형태

powder

색상

white to off-white

저장 온도

−20°C

SMILES string

[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC3)[C@H](C)CC\C=C(/C)C

InChI

1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1

InChI key

CAHGCLMLTWQZNJ-BQNIITSRSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Lanosterol, an amphipathic molecule, that is produced by lanosterol synthase (LSS). It is enriched in the lens.

애플리케이션

Lanosterol has been used:
  • as a standard in HPLC for the quantification in testis samples
  • in S-adenosyl-L-methionine:Δ24-sterol-C-methyltransferase (SMT) assay
  • to treat wild-type cells growing in rich medium to know its effects on Sre1 protein

생화학적/생리학적 작용

Cholesterol precursor sterol.
Lanosterol serves as an endogenous selective modulator of macrophage immunity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

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Sigma-Aldrich

E6510

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T-MAS

Fucosterol ≥93%

Sigma-Aldrich

F5379

Fucosterol

5α-Cholest-7-en-3β-ol

Sigma-Aldrich

C3652

5α-Cholest-7-en-3β-ol

Lorena Fernández-Cabezón et al.
Frontiers in microbiology, 9, 958-958 (2018-06-06)
Nowadays steroid manufacturing occupies a prominent place in the pharmaceutical industry with an annual global market over $10 billion. The synthesis of steroidal active pharmaceutical ingredients (APIs) such as sex hormones (estrogens, androgens, and progestogens) and corticosteroids is currently performed
Lanosterol reverses protein aggregation in cataracts
Zhao L, et al.
Nature, 523(7562), 607-607 (2015)
Identification and Characterization of an S-Adenosyl-L-methionine:-Sterol-C-methyltransferase cDNA from Soybean
Shi J, et al.
The Journal of Biological Chemistry, 271(16), 9384-9389 (1996)
Marja-Riitta Taskinen et al.
Journal of clinical lipidology, 14(1), 77-87 (2020-01-10)
Monoclonal antibodies to proprotein convertase subtilisin/kexin type 9 (PCSK9) significantly lower the levels of low-density lipoprotein and very-low-density lipoproteins (VLDL), but their effect on postprandial lipoprotein metabolism in dyslipidemic subjects is unclear. This study aimed to investigate the effects of
Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast
Porter J R, et al.
The Journal of Biological Chemistry, 285(52), 41051-41061 (2010)
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