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Merck
모든 사진(4)

주요 문서

S1270

Sigma-Aldrich

β-Sitosterol

synthetic, ≥95%

동의어(들):

beta-Sitosterol, α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol

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About This Item

실험식(Hill 표기법):
C29H50O
CAS Number:
Molecular Weight:
414.71
Beilstein:
1916165
EC Number:
MDL number:
UNSPSC 코드:
12352211
PubChem Substance ID:
NACRES:
NA.77

생물학적 소스

synthetic

Quality Level

분석

≥95%

형태

powder

mp

136-140 °C (lit.)

작용기

hydroxyl

배송 상태

ambient

저장 온도

−20°C

SMILES string

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC

InChI

1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key

KZJWDPNRJALLNS-VJSFXXLFSA-N

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관련 카테고리

애플리케이션

β-Sitosterol has been used:
  • to study its ability to improve the suitability of two pollens
  • as a standard in the determination of sterol purities
  • as a standard in quantitative genetic analysis
  • as a standard in the estimation of plant sterols

생화학적/생리학적 작용

A phytosterol with structure very similar to cholesterol that exhibits estrogenic activity. Inhibits proliferation of human leukemia cells, with G2/M arrest, endoreduplication, and polymerization of α-tubulin and microtubules.
Increased β-sitosterol administration displaces cholesterol during absorption. This elevates fecal secretion. It is known to regulate intestinal immunity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Polymeric Biomaterials: Medicinal and Pharmaceutical Applications, 2, 162-162 (2013)
Essence of Anesthesia Practice E-Book, 657-657 (2010)
Dong-Oh Moon et al.
Cancer letters, 264(2), 181-191 (2008-03-04)
beta-Sitosterol (SITO) is a potentially valuable candidate for cancer chemotherapy, however the cellular and molecular mechanisms responsible for its anti-cancer activity are unknown. Therefore, we attempted to elucidate the mechanisms responsible for SITO-induced anti-proliferation in human leukemia cells. Treatment with
Sterol limitation in a pollen-fed omnivorous lady beetle (Coleoptera: Coccinellidae)
Pilorget L, et al.
Journal of Insect Physiology, 56(1), 81-87 (2010)
Using theoretical correction factors for quantitative analysis of sterols and sterol concentrates
Costin CD, et al.
Journal of the American Oil Chemists' Society, 86(2), 111-118 (2009)

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