추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
GB-69, monoclonal
포함
15 mM sodium azide
종 반응성
wide range
기술
dot blot: suitable
immunofluorescence: suitable
immunohistochemistry: 1:100-1:200 (Using heat-retrieved formalin-fixed, paraffin-embedded human brain and/or cerebellum sections.)
indirect ELISA: suitable
동형
IgG1
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
mouse ... Gabra1(14394)
일반 설명
γ-Aminobutyric acid (GABA) functions as an inhibitory neurotransmitter in the central nervous system. It also functions as a neuromodulator in some peripheral tissues. Additionally, GABA is present in non-nervous tissues and regulates blood pressure, heart rate, respiration, immunomodulation, cell proliferation, protein synthesis and metabolism.
Monoclonal Anti-GABA (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. The antibody does not cross react with L-α-aminobutyric acid, L-glutamic acid, L-aspartic acid, glycine, δ-aminovaleric acid, L-threonine, L-glutamine, taurine, putrescine, L-alanine and carnosine. However, weak cross-reaction is observed with β-alanine and ε-aminocaproic acid.
Monoclonal Anti-GABA (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. The antibody does not cross react with L-α-aminobutyric acid, L-glutamic acid, L-aspartic acid, glycine, δ-aminovaleric acid, L-threonine, L-glutamine, taurine, putrescine, L-alanine and carnosine. However, weak cross-reaction is observed with β-alanine and ε-aminocaproic acid.
Monoclonal Anti-GABA (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system and a neuromodulator in certain peripheral tissues. GABA is also present in non-nervous structures.
면역원
GABA (γ-aminobutyric acid) conjugated to BSA
애플리케이션
Monoclonal Anti-GABA antibody produced in mouse has been used in immunohistochemistry and immunocytochemistry.
생화학적/생리학적 작용
γ-Aminobutyric acid (GABA) mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
물리적 형태
Supplied as ascites fluid with 15 mM sodium azide as preservative.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Newborn horizontal cells migrate bi-directionally across the neuroepithelium during retinal development
Edqvist PHD and Hallbook F
Development, 131(6), 1343-1351 (2004)
Structure, function, and modulation of GABAA receptors
Sigel E and Steinmann ME
The Journal of Biological Chemistry, 287(48), 40224-40231 (2012)
Christine J Huh et al.
eLife, 5 (2016-10-18)
Aging is a major risk factor in many forms of late-onset neurodegenerative disorders. The ability to recapitulate age-related characteristics of human neurons in culture will offer unprecedented opportunities to study the biological processes underlying neuronal aging. Here, we show that
Teruyuki Fukushima et al.
Journal of neurophysiology, 102(3), 1459-1471 (2009-04-17)
Analgesic effects of serotonin (5-hydroxytryptamine [5-HT]) type 3 (5-HT3) receptors may involve the release of gamma-aminobutyric acid (GABA) in the spinal dorsal horn. However, the precise synaptic mechanisms for 5-HT3 receptor-mediated spinal analgesia are not clear. In this study, we
Per-Henrik D Edqvist et al.
Development (Cambridge, England), 131(6), 1343-1351 (2004-02-20)
Cell migration plays an important role during the development of the retina. In this work we have studied the migration of newborn horizontal cells in avian embryonic retina. Using the pattern of the early expressed transcription factors Lim1 and Prox1
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