A1164

Azaserine

Hybri-Max^™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

• 동의어(들): O-Diazoacetyl-L-serine
• 실험식(Hill 표기법): C₅H₇N₃O₄
• CAS Number: 115-02-6
• Molecular Weight: 173.13
• Beilstein: 1726602
• EC Number: 204-061-6
• MDL number: MFCD00036802
• UNSPSC 코드: 12352207
• PubChem Substance ID: 24890511
• NACRES: NA.75

속성

• Grade: Hybri-Max^™
• Quality Level: 200
• 무균: γ-irradiated
• 제품 라인: BioXtra
• 양식: lyophilized powder
• 기술: cell culture | hybridoma: suitable
• 불순물: endotoxin, tested
• 항생제 활성 스펙트럼: fungi
• 동작 모드: enzyme | inhibits
• 저장 온도: −20°C
• SMILES string: N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O
• InChI: 1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
• InChI key: MZZGOOYMKKIOOX-VKHMYHEASA-N

설명

일반 설명

Chemical structure: amino acid derivatives

애플리케이션

For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.

생화학적/생리학적 작용

Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.

재구성

Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.

법적 정보

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H351
• 예방조치 성명서: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges