추천 제품
생물학적 소스
bovine
Quality Level
분석
≥98% (agarose gel electrophoresis)
양식
lyophilized powder
분자량
~66 kDa
정제법
heat shock fractionation
포장
poly bottle of
기원
USA origin
기술
ELISA: suitable
불순물
essentially globulin free
≤1 ng/mg endotoxin
pH
5.2
solubility
water: soluble (40 mg/ml)
UniProt 수납 번호
외래 활성
BT Virus, none detected
VSV Virus, none detected
저장 온도
2-8°C
유전자 정보
bovine ... ALB(280717)
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일반 설명
Bovine Serum Albumin (BSA) is a globular non-glycosylated protein that encompasses structurally distinct domains (I, II, and III) with two sub-domains, A and B within each domain. Structurally, BSA is an α-helical protein with 17 cysteine residues.
애플리케이션
Bovine Serum Albumin has been used:
- as a component of the minimal liquid medium to culture Porphyromonas gingivalis strains
- as a standard protein to quantify microsomes homogenate using Bradford method
- as a blocking agent in enzyme-linked immunosorbent assay (ELISA) of fecal lactoferrin
생화학적/생리학적 작용
Bovine Serum Albumin (BSA) is widely used in drugs and antibody delivery. It also finds applications in nanoparticle preparations and is useful in targeting tumor tissues. BSA is non-immunogenic and non-toxic. It also shows binding with metal ions.
Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.
특징 및 장점
- Low endotoxin
- Essentially globulin-free
제조 메모
Prepared using heat shock fractionation
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
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