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Merck
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Key Documents

A3401

Sigma-Aldrich

Ala-Ala-Phe-7-amido-4-methylcoumarin

protease substrate

동의어(들):

H-Ala-Ala-Phe-AMC

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About This Item

실험식(Hill 표기법):
C25H28N4O5
CAS Number:
Molecular Weight:
464.51
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

분석

≥98% (TLC)

형태

powder

solubility

ethanol: 20 mg/mL, clear, colorless to light yellow

저장 온도

2-8°C

SMILES string

CC(N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C25H28N4O5/c1-14-11-22(30)34-21-13-18(9-10-19(14)21)28-25(33)20(12-17-7-5-4-6-8-17)29-24(32)16(3)27-23(31)15(2)26/h4-11,13,15-16,20H,12,26H2,1-3H3,(H,27,31)(H,28,33)(H,29,32)

InChI key

FVRLYIFIDKXFHU-UHFFFAOYSA-N

일반 설명

Ala-Ala-Phe-7-amido-4-methylcoumarin is a fluorogenic substrate for the proteolytic activity. It is a positively charged substrate molecule.

애플리케이션

Ala-Ala-Phe-7-amido-4-methylcoumarin has been used:
  • in the preparation of the reaction mixture for enzymatic assays
  • to initiate the enzyme reaction in tripeptidyl peptidase-1 (TPP1) enzyme activity assay
  • to initiate the assay reaction in lysosomal hydrolases activity assay

기질

Substrate for chymotrypsin and tripeptidyl peptidaseII.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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