추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
fractionated antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
human
포장
vial of 2 mL lyophilized antiserum
기술
indirect ELISA: 1:25,000
UniProt 수납 번호
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... SERPINC1(462)
일반 설명
Antithrombin III (ATIII) is a small glycoprotein produced by the liver that functions as a serine protease inhibitor to block coagulation.
Antithrombin III is a 58kDa glycoprotein synthesized in the liver. It has two domains, a heparin-binding domain and target protease binding domain.
면역원
human antithrombin III
애플리케이션
Anti-Antithrombin III antibody has been used in western blotting and antigenic assay.
생화학적/생리학적 작용
Antithrombin III is a serine protease inhibitor which affects many intrinsic and extrinsic blood coagulation pathways. It inactivates the function of thrombin and factor X in blood. Severe sepsis is caused due to lack of antithrombin III.
물리적 형태
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
재구성
Reconstitute with 2 mL deionized water.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Eye Dam. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
High-dose antithrombin III in severe sepsis: a randomized controlled trial
Warren B L, et al.
JAMA : The Journal of the American Medical Association, 286(15), 1869-1878 (2001)
Carlos Bravo-Pérez et al.
American journal of hematology, 97(2), 216-225 (2021-11-21)
Antithrombin deficiency, the most severe thrombophilia, might be underestimated, since it is only investigated in cases with consistent functional deficiency or family history. We have analyzed 444 consecutive, unrelated cases, from 1998 to 2021, with functional results supporting antithrombin deficiency
Maria Eugenia de la Morena-Barrio et al.
Blood, 140(2), 140-151 (2022-04-30)
Antithrombin deficiency, the most severe congenital thrombophilia, might be underestimated, as some pathogenic variants are not detected by routine functional methods. We have identified 2 new SERPINC1 variants, p.Glu227Lys and p.Asn224His, in 4 unrelated thrombophilic patients with early and recurrent
Sean P Harrison et al.
Experimental & molecular medicine, 55(9), 2005-2024 (2023-09-01)
The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, including the liver. Current organoid
María E de la Morena-Barrio et al.
American journal of hematology, 96(11), 1363-1373 (2021-07-30)
Atresia of inferior vena cava (IVC) is a rare congenital malformation associated with high risk of venous thrombosis that still has unknown etiology, although intrauterine IVC thrombosis has been suggested to be involved. The identification of IVC atresia in a
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