B9031

(−)-Bilobalide from Ginkgo biloba leaves

≥93% (HPLC)

• 동의어(들): Bilobalide
• 실험식(Hill 표기법): C₁₅H₁₈O₈
• CAS Number: 33570-04-6
• Molecular Weight: 326.30
• MDL number: MFCD00238547
• UNSPSC 코드: 85151701
• PubChem Substance ID: 24892116
• NACRES: NA.28

속성

• 생물학적 소스: plant leaves (Ginkgo biloba)
• 분석: ≥93% (HPLC)
• 형태: powder
• 기술: HPLC: suitable
• 색상: white
• 저장 온도: −20°C
• SMILES string: CC(C)(C)[C@]1(O)CC2OC(=O)C[C@@]23C(=O)OC4OC(=O)[C@H](O)[C@]134
• InChI: 1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
• InChI key: MOLPUWBMSBJXER-YDGSQGCISA-N

설명

일반 설명

Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted from Ginkgo biloba. It is synthesized from geranylgeranyl pyrophosphate (GGPP).

애플리케이션

(-)-Bilobalide from Ginkgo biloba leaves has been used as a reference substance to study the antimicrobial activity of different fractions of G.biloba leaves against a number of Gram-positive and negative bacteria and yeasts.

생화학적/생리학적 작용

Bilobalide is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. It exhibits neuroprotective, anti-inflammatory, anti-oxidative and anti-apoptotic properties. Bilobalide, a γ-aminobutyric acid (GABA) A_A-rho, 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist, may be used to study the function of these receptors in the brain processes such as cognition and memory. It serves as a specific platelet-activating factor receptor antagonist, which helps in the treatment of cardiovascular (Alzheimer′s disease) and cerebrovascular diseases.

Bioactive terpenoid found in Ginkgo biloba.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)