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Merck
모든 사진(1)

주요 문서

D0195

Sigma-Aldrich

Dimethylethylammoniumpropane sulfonate

≥97% (TLC)

동의어(들):

NDSB 195

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About This Item

실험식(Hill 표기법):
C7H17NO3S
CAS Number:
Molecular Weight:
195.28
UNSPSC 코드:
12161900
NACRES:
NA.25

설명

zwitterionic

Quality Level

분석

≥97% (TLC)

형태

powder

분자량

195.28 g/mol

기술

LC/MS: suitable
protein quantification: suitable

색상

white

응용 분야

detection

저장 온도

room temp

일반 설명

Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization.

애플리케이션

Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions.
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

기타 정보

This product is non-micelle forming.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리 방문

Thermoreversible hydrogels XIII: Synthesis and swelling behaviors of [N-isopropylacrylamide-co-sodium 2-acrylamido-2-methylpropyl sulfonate-co-N,N-dimethyl(acrylamido propyl) ammonium propane sulfonate] copolymeric hydrogels
Lee, W. and W. Yuan
Journal of Polymer Research, 7, 29-29 (2000)
A E Ochem et al.
The Journal of biological chemistry, 272(47), 29919-29926 (1997-12-31)
The Ku antigen consists of two subunits of 70 and 83 kDa and is endowed with both duplex DNA end-binding capacity and helicase activity (human DNA helicase II). HeLa Ku can be isolated from in vitro cultured human cells uniquely
L Vuillard et al.
FEBS letters, 353(3), 294-296 (1994-10-24)
The potential usefulness of the new zwitterionic solubilizing agent, dimethyl ethylammonium propane sulfonate (NDSB195), in protein crystallization was shown using hen egg-white lysozyme. In the presence of this agent, highly diffracting crystals were obtained using ammonium sulphate as a precipitant

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