D0754
3,5-Diiodo-L-tyrosine dihydrate
≥98.0% (HPLC), suitable for ligand binding assays
동의어(들):
3,5-diiodo-L-tyrosine hydrate (1:2)
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H9I2NO3 · 2H2O
CAS Number:
Molecular Weight:
469.01
Beilstein:
2218691
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
추천 제품
제품명
3,5-Diiodo-L-tyrosine dihydrate, crystalline
분석
≥98.0% (HPLC)
Quality Level
양식
crystalline
기술
ligand binding assay: suitable
색상
white
mp
200 °C (dec.) (lit.)
solubility
4 M NH4OH in methanol: 50 mg/mL, clear, yellow-green
저장 온도
−20°C
SMILES string
N[C@@H](Cc1cc(I)c(O)c(I)c1)C(O)=O
InChI
1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
InChI key
NYPYHUZRZVSYKL-ZETCQYMHSA-N
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애플리케이션
Substrate for the assay of halogenated tyrosine and thyroid hormone aminotransferase. Intermediate in the biosynthesis and alternative pathways of metabolism of thyroid hormones.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Yining Zheng et al.
Talanta, 69(1), 107-112 (2008-10-31)
In this paper, a new method for separation, identification and quantitation of iodotyrosines and iodothyronines [3-monoiodo-L-tyrosine (MIT), 3,5-diiodo-L-tyrosine (DIT), L-thyronine (T(0)), 3,5-diiodo-L-thyronine (T(2)), 3,5,3'-triiodo-L-thyronine (T(3)) and 3,3',5,5'-tetraiodo-L-thyronine (T(4))] was described by using capillary electrophoresis with photodiode-array ultraviolet-visible detection (CE-UV). The
Jana Frýdlová et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 863(1), 135-140 (2008-02-08)
The interaction of porcine pepsin A with immobilized derivatives of aromatic amino acids was investigated. Divinyl sulfone-activated Sepharose was used to immobilize N-acetyl-l-phenylalanine and 3,5-diiodo-l-tyrosine via their free carboxyl groups and l-tyrosine via its amino group. Immobilized l-tyrosine was iodinated
Sangeeta Kumari et al.
Journal of the American Society for Mass Spectrometry, 18(8), 1516-1524 (2007-06-26)
L-Tyrosine and iodinated L-tyrosines, i.e., 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine, are successfully used as chiral references for the chiral discrimination of aliphatic, acidic, and aromatic amino acids. Chiral discrimination is achieved by investigating the collision-induced dissociation spectra of the trimeric complex [Cu(II)(ref)(2)(A)
Purification and properties of halogenated tyrosine and thyroid hormone transaminase from rat kidney mitochondria.
M Nakano
The Journal of biological chemistry, 242(1), 73-81 (1967-01-10)
A Balsam et al.
The Journal of clinical investigation, 72(4), 1234-1245 (1983-10-01)
Studies were performed to elucidate the nature of the pathway of hepatic thyroxine (T4) metabolism that is activated by inhibitors of liver catalase. For this purpose, the metabolism of T4 in homogenates of rat liver was monitored with T4 labeled
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