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제품명
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide, ≥99% (HPLC), solid
Quality Level
분석
≥99% (HPLC)
양식
solid
색상
red
mp
267 °C (dec.) (lit.)
solubility
DMSO: 0.5 mg/mL
methanol: soluble
εmax
36.0-41.0 at 457-463 nm in methanol
응용 분야
diagnostic assay manufacturing
hematology
histology
저장 온도
2-8°C
SMILES string
[I-].CC[n+]1ccccc1\C=C\c2ccc(cc2)N(C)C
InChI
1S/C17H21N2.HI/c1-4-19-14-6-5-7-17(19)13-10-15-8-11-16(12-9-15)18(2)3;/h5-14H,4H2,1-3H3;1H/q+1;/p-1
InChI key
AMAXNNVXIBDEMV-UHFFFAOYSA-M
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애플리케이션
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish.
생화학적/생리학적 작용
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) accumulates in the mitochondria and has a large fluorescence Stokes shift. It is also used for the relative measurements of mitochondrial membrane potential.
Suitable as a mitochondrial stain in live cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.
Vlasits AL, et al.
Hearing Research, 294, 153-165 (2012)
Ru Zhang et al.
Biomolecules, 10(10) (2020-10-22)
Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists. In the present study, we
Marina Yoffe et al.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(7-8), 511-517 (2020-05-22)
The lateral line is the primary modality fish use to create a hydrodynamic image of their environment. These images contribute to a variety of behaviors, from rheotaxis to escape responses. Here we discern the contributions of visual and lateral line
Development of a no-wash assay for mitochondrial membrane potential using the styryl dye DASPEI.
Jensen KH and Rekling JC
Journal of Biomolecular Screening, 15, 1071-1081 (2010)
W Armand Guiguemde et al.
Nature, 465(7296), 311-315 (2010-05-21)
Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year worldwide. Vaccine development has proved difficult and resistance has emerged for most antimalarial drugs. To discover new antimalarial chemotypes, we have used a phenotypic
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